Humans are constantly exposed to a huge number of environmental factors that may be linked to potential toxicities via multiple mechanisms and biological processes.
How does toxicology deal with this complex reality today?
The vision of SysTox is to use computational models, that offer a great alternative approach to animal testing for a better understanding of the adverse health effects from exposure.
We develop and apply integrative systems biology & bioinformatics methods to explore and predict the complexity of the biology on both integrative and systemic levels. SysTox leads and is involved in several French and European projects.
The SysTox group, led by Karine Audouze, is part of the MetaTox team of the Inserm T3S Lab (UMRS 1124) at the Université de Paris.
The systox group will participate in the GDRO3 annual meetings. A study on pharmacophores will be presented.
The systox group will participate in the GGMM-SFCI Conference 2021 which will take place from September 29th to October 1st, 2021. On this occasion, several members of the group will present a poster of their work.
Hackathon day with the full team to create the first SysTox web site!
The systox group have participated in the Oberon 2021 virtual Annual Meeting on the 22nd and 23rd of April 2021.
The SysTox group have participated in the Tour des Sciences 2020 during the Paris stage on the 29th October 2020. During this popular science event, the SysTox group presented its work on Adverse Outcome Pathways (AOP). The concept of AOP was presented through a...
Here find our last publications