Research

Ongoing projects

PARC

The European Partnership for the Assessment of Risks from Chemicals aims to develop next-generation chemical risk assessment to protect human health and the environment. It supports the European Union’s Chemicals Strategy for Sustainability and the European Green Deal’s “Zero pollution” ambition.

RadoNorm

RadoNorm: H2020 project – Towards effective radiation protection based on improved scientific evidence and social considerations – focus on Radon and NORM

Exposome Booster Program

This Booster program combines multiple approaches to identify associations between components of the exposome and health events at multiple scales but also to better define causal links between them.

FUSION

ANR/DFG collaborative Franco-german project that focus on SDHi (succinate dehydrogenase inhibitors), a family of fungicides. The overall objective is to fill a large gap of knowledge regarding the neurodevelopemental toxicity of SHDi fungicides using an integrated approach and several complementary in vivo, in vitro and in silico (AOP development) models.

IA-COPc

Artificial intelligence to assess the impact of the chemical exposome on breast cancer and its societal cost: towards an integrated and interdisciplinary approach for public health.

ENDOFAT

The ENDOFAT project will study the interactions between xenobiotics, adipose tissue and endometriotic lesions using an integrative approach.

ScoreDockPolariz

ANR project to develop a novel accurate empirical scoring function for virtual screening and drug discovery. In vitro screening will also be applied on both catalytic and PPI sites to cross-validate the in silico predictions and to identify new valuable small molecules.

Platforms

iPOP-UP

iPOP-UP website is dedicated to host the shared knowledge of the Université Paris Cité bioinformatic community. It aims to gather tutorials, courses and presentations of events related to bioinformatics to make this field more accessible to students and researchers.

France Exposome

France Exposome supports research in the environmental health field, leading to a better understanding of the existing associations between chemical exposures and health outcomes related to chronic diseases.

ELIXIR Toxicology

The ELIXIR Toxicology community is co-leaded by SysTox (K. Audouze). The main goal is to support the integration of standards, tools and resources to support toxicology research projects and risk governance at the national and international levels.

Completed projects

HERA

HERA : H2020 project – The overall aim of the HERA project is to set the priorities for an envionment, climate and health reserach agenda in the EU.

HBM4EU

HBM4EU: H2020 project with the aim of coordinating and advancing human biomonitoring in Europe to provide evidence for chemical policy making.

TABAC

INCa et IRESP project: Co-exposure to cigarette smoke and tumor microenvironment & breast cancer aggressiveness.

MULTIMIX

MULTIMIX: ANR project – Multidisciplinary approach to better understand aroma perception of flavor mixture.

ReadEDTest

A self-questionnaire to enable researchers to assess the status of their in vitro test for endocrine disruptors.

CREATIvE

CREATIvE : ANR project coordinated by the SysTox group. Systems toxicology of pollutant mixture released from grafted adipose tissue.

Neurophyto

Ecophyto II+ plan : Study of the effects from exposure to agrochemicals on the cognitive and psychomotor development of children.

OBERON

OBERON: H2020 project coordinated by the SysTox group. The aim of the project is to build an integrated approach for testing and assessment (IATA) to detect endocrine disruptors-related metabolic disorders by developing, improving and validating a battery of test systems. Project part of the EURION cluster.